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. 2016 Aug 10;7(37):60230–60244. doi: 10.18632/oncotarget.11176

Figure 5. CXCR4 abolishes the effects of miR-126 on RhoA signaling pathway in colon cancer.

Figure 5

(A) Western blot analysis of the expression levels of components of the RhoA signaling pathway. Left panels show expression levels in HCT116/miR-126 cells after transient transfection with the CXCR4 plasmids. Right panels show expression levels in SW480/anti-miR-126 cells after exposure to AMD3100 (1000 ng/ml). (B) RhoA activation G-LISA assays were used to measure RhoA activity in HCT116/miR-126 cells transiently transfected with the CXCR4 plasmids (left panels) and in SW480/anti-miR-126 cells exposed to 1000 ng/ml AMD3100 (right panels). *p < 0.05, ***p < 0.001.