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. 2016 Aug 5;7(37):60432–60445. doi: 10.18632/oncotarget.11080

Figure 9. Bod1 overexpression inhibits X-ray-induced premature chromatid separation and enhances resistance to radiation in 786-O and A549 cells.

Figure 9

A. Proportion of 786-O and A549 cells with premature chromatid separation after transfection with Bod1 overexpression vector or negative vector and exposure to 4 Gy X-rays. B. Cell proliferation in 786-O and A549 cells 1, 2, 3, or 4 days after transfection with Bod1 overexpression vector or negative vector and exposure to 4 Gy X-rays were measured by MTT assay. C. Survival in 786-O and A549 cells transfected with Bod1 overexpression vector or negative vector and then exposed to 0, 1, 2, 4, or 6 Gy X-rays measured by colony formation assay. D. Micronucleus counts in 786-O and A549 cells transfected with Bod1 overexpression vector or negative vector and exposed to 2 or 4 Gy X-rays. E. Survival in 786-O and A549 cells co-transfected with miR-142-3p and Bod1 overexpression vector and then exposed to 0, 1, 2, 4, or 6 Gy X-rays measured by colony formation assay. Each data point represents the mean of three separate experiments; bars indicate standard errors. *P < 0.05; **P < 0.01.