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. 2016 Aug 12;7(37):60593–60608. doi: 10.18632/oncotarget.11260

Figure 7. Barx2 inhibits the proliferation, migration, and invasion of GC cells by negatively regulating the Wnt/β-catenin signaling pathway.

Figure 7

a. WB analysis of the association between expression levels of Barx2 and β-catenin in total cellular, nuclear, and cytoplasmic fractions isolated from BGC-823 cells at 48 h after transfection with Barx2 overexpression or the control empty vector. BGC-823 cells with Barx2 overexpression or vector control were grown in media with or without 200 ng/ml inhibitor of Wnt signaling Dickkopf-related protein 1 (Dkk1); CCK-8 assays b., wound healing c. and transwell assays d. were used to examine the GC cells’ proliferation, migration, and invasion ability, respectively. (* P<0.05, # P>0.05).