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. 2016 Jul 26;7(37):60712–60722. doi: 10.18632/oncotarget.10858

Table 1. Ongoing trials studying the role of mTOR inhibitors in TNBC.

TRIAL REGISTRATION NUMBER INVESTIGATOR INSTITUTION
Phase Ib/II Trials of RDA001 in Triple Negative Metastatic Breast Cancer NCT01939418 National Cancer Center, Korea
A study of Lapatinib in combination with Everolimus in patients with Advanced, Triple Negative Breast Cancer NCT01272141 Emory University Winship Cancer Institute
Liposomal Doxorubicin, Bevacizumab and Temsirolimus (DAT) in Triple-Negative Breast Cancer (TNBC) Insensitive to Standard Neoadjuvant chemotherapy NCT02456857 M.D. Anderson Cancer Center
Comparison of Single-Agent Carboplatin vs the Combination of Carboplatin and Everolimus for the Treatment of Advanced Triple-Negative Breast Cancer NCT02531932 Icahn School of Medicine at Mount Sinai
Eribulin Mesylate and Everolimus in Treating Patients With Triple-Negative Metastatic Breast Cancer NCT02120469 City of Hope Medical Center
NECTAR Everolimus Plus Cisplatin (-) Breast Cancer (NECTAR) NCT01931163 The Methodist Hospital System
Safety and Tolerability of Everolimus in Combination With Eribulin in Triple-negative Breast Cancer NCT02616848 Istituti Ospitalieri di Cremona
A Study of AZD2014 in Combination With Selumetinib in Patients With Advanced Cancer (TORCMEK) NCT02583542 Queen Mary University of London