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EC50 values for AZA and DAC on NSCLC cell viability
| AZA EC50 ± SEM (μM) | DAC EC50 ± SEM (μM) | |
|---|---|---|
| A549 | 6.3 ± 1.1 | >25 |
| H1975 | 8.6 ± 2.9 | >25 |
| H460 | 1.8 ± 0.3 | >25 |
| H23 | 10.5 ± 1.8 | >25 |
| H1299 | 5.1 ± 0.2 | 5.9 ± 2.1 |
Note: EC50 values were calculated from 3 independent experiments using Graphpad Prism software.
Abbreviations: AZA, azacitidine; DAC, decitabine; NSCLC, non-small cell lung cancer.
