Table 1.
Intraocular injection details
| AAV serotype | NHP ID | Right versus left eye | Dose (vg) | Volume injection (μL) | Other |
|---|---|---|---|---|---|
| Intravitreal | |||||
| AAV8b | 05D 370 | Left | 1E + 09 | 150 | |
| 05C 028 | Left | 1E + 10 | 150 | ||
| 9986 | Right | 1E + 11 | 150 | ||
| 9986 | Left | 1E + 12 | 150 | ||
| AAV7m8 | 05C 068 | Right | 1E + 08 | 150 | |
| 07D 179 | Left | 1E + 09 | 150 | ||
| 05C 028 | Right | 1E + 10 | 150 | ||
| 5098 | Right | 1E + 11 | 150 | ||
| 9820 | Right | 1E + 12 | 150 | Injection over fovea | |
| 9820 | Left | 6.67E + 11 | 100 | ||
| Subretinal | |||||
| AAV8b | 04C094 | Right | 1.0E + 10 | 150 | |
| 04C 076 | Left | 1.5E + 11 | 150 | ||
| 99-09 | Right | 1E + 12 | 150 | ||
| 99-09 | Left | 1E + 12 | 150 | SR (50)/IV (100) | |
| AAV7m8 | O4C094 | Left | 1.0E + 10 | 150 | |
| 9817 | Right | 5.33E + 10 | 80 | ||
| 04C 076 | Right | 1.5E + 11 | 150 | Focal hemorrhage at retinotomy site | |
| 5285 | Right | 1E + 12 | 150 | ||