Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 16;18:175. doi: 10.1186/s12864-017-3544-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 1 — Taf14 negatively regulated genes show distinct regulatory features. These genes are mostly stress-related, their promoters mainly contain a TATA box and SAGA complex is mostly responsible for loading TBP to these promoters. Transcription of these genes is also highly regulated by a distinct set of regulators. Besides positive regulation by the stress related activator Msn2/4, transcription regulation of Taf14 repressed promoters is dominated by negative regulators of transcription. These include the negative co-regulators histone de-acetylases (Hda1 and Rpd3), TBP repressors Mot1 and NC2 (Ncb2-Bur6), Cyc8-Tup1 repressor complex, and two members of Mediator complex, Srb10 and the Mediator tail module. Repressing elements of transcription are illustrated in red and activating elements are in green