Figure 4.

Fast ssDNA translocation statistics. (a) Mean current blockage vs dwell time scatter plot for n = 2008 100-nt ssDNA translocation events through Pore 1 at 5 MHz, 1 MHz and 200 kHz filtering bandwidths (n indicated for the 5 MHz filtering bandwidth). Filtering to lower frequencies clearly indicates increased attenuation especially for events close to the inverse of the filter’s cutoff frequency. (b) Histogram plot of counts vs dwell time for the data presented in (a). Each of the plots are fitted to A₁e^−t/τ₁ + A₂e^−t/τ₂ and τ₁ is indicated for each of the fits where τ₁ < τ₂. Increasing the filtering bandwidth indicates a reduction in the characteristic dwell time for the event suggesting that even at bandwidths as high as 1 MHz, translocation events were distorted.