Table 2.
Deferral rates related to malaria exposure in the American continent
| Country | Location and period | Period | Subjects | Sample size | Deferral cause | Findings | Reference |
|---|---|---|---|---|---|---|---|
| Canada | Nationwide data, except Québec | 2007–2012 | Candidate blood donors | 1,625,432 | Travel to endemic countries | 76,312 deferred subjects | O’Brien et al. [26] |
| USA | Six blood centres located in San Francisco (CA), Milwaukee (WI), Cincinnati (OH), Pittsburgh (PA), Dedham (MA) and Douglasville (GA) | 2006 | Overall deferred donors due to travel to endemic countries | 2108 | Travel to Mexico | 885 deferred donors | Spencer et al. [31] |
| USA | Six blood centres located in San Francisco (CA), Milwaukee (WI), Cincinnati (OH), Pittsburgh (PA), Dedham (MA) and Douglasville (GA) | 2006 | Overall non-eligible donors at moment | 13,007 | Travel to endemic countries | 2108 deferred subjects | Spencer et al. [30] |
| Canada | Nationwide data | Jul to Dec 2004 | Candidate blood donors | 37,165 | Travel to endemic countries | 1105 deferred subjects | O’Brien et al. [25] |
| USA | Nationwide data | 2000–2006 | Candidate blood donors | 28,933,936 | Travel to endemic countries | 316,495 deferred subjects | Leiby et al. [24] |
| USA | Mississippi Valley Regional Blood Center | Apr 2004 to Mar 2005 | Candidate blood donors | NA | Travel or residence in endemic countries | 156 deferred subjects | Katz et al. [23] |
| USA | Six blood centres located in San Francisco (CA), Milwaukee (WI), Cincinnati (OH), Pittsburgh (PA), Dedham (MA) and Douglasville (GA) | 2003 | Candidate blood donors | NA | Travel to endemic countries | 12,310 deferred subjects | Spencer et al. [29] |
| Brazil | Manaus | NA | Candidate blood donors | 324 | Previous history of malaria | 38 deferrals | Torres et al. [32] |
| Colombia | Cali | 2002 | Candidate blood donors | 286 | Travel or living in endemic areas in the last year | 115 deferrals | Castillo et al. [22] |
| Canada | Nationwide data | 2002 | Candidate blood donors | NA | Travel to endemic countries | 7216 deferred subjects | Shehata et al. [28] |
| Brazil | São Paulo (SP) | NA | Candidate blood donors | 1200 | Travel to endemic areas without prophylaxis in the last 6 months, living in malaria endemic areas (deferral for 3 years), previous malaria in the lifetime | 36 deferred subjects | Sáez-Alquézar et al. [27] |
| Brazil | Belém (PA) | NA | Candidate blood donors | 250 | Travel to endemic area in the last 6 months, previous malaria in the last year or fever in the last 30 days | 12 deferred subjects | Sáez-Alquézar et al. [27] |
| Brazil | Matupá and Peixoto de Azevedo (MT) | NA | Candidate blood donors | 31 | Fever in the last 30 days | No deferrals | Sáez-Alquézar et al. [27] |
NA non-available information