Table 5.
Factors related to death from transfusion-transmitted malaria in the American continent
| Variable | Death (number, %) | Discharge (number, %) | OR (95% CI) | p |
|---|---|---|---|---|
| Living in an endemic country | ||||
| Yes | 5 (27.8) | 215 (67.4) | – | 1 |
| No | 13 (72.2) | 104 (32.6) | 0.19 (0.06–0.54) | 0.002 |
| Sex | ||||
| Male | 5 (83.3) | 16 (43.2) | – | 1 |
| Female | 1 (16.7) | 21 (56.8) | 6.56 (0.70–61.86) | 0.100 |
| Age group (in years) | ||||
| >60 | 2 (50.0) | 8 (21.6) | – | 1 |
| 31–60 | 2 (50.0) | 6 (16.2) | 0.75 (0.068–6.96 | 0.800 |
| 16–30 | 0 (0.0) | 7 (18.9) | 4.41 (0.18–107.29) | 0.362 |
| ≤15 | 0 (0.0) | 16 (43.2) | 9.71 (0.42–225.85) | 0.157 |
| Transfusion indication | ||||
| Gyneco-obstetrical conditions | 0 (0.0) | 34 (49.3) | – | 1 |
| Surgical procedures | 5 (62.5) | 24 (34.8) | 0.06 (0.01–1.22) | 0.068 |
| Complications from neoplasias | 2 (25.0) | 3 (4.3) | 0.02 (<0.01–0.51) | 0.018 |
| Haemoglobinopathies | 0 (0.0) | 2 (2.9) | 0.07 (<0.01–4.48) | 0.212 |
| Nephropathy-associated anaemia | 0 (0.0) | 2 (2.9) | 0.07 (<0.01–4.48) | 0.212 |
| Other causes of anaemia | 1 (12.5) | 4 (5.8) | 0.04 (<0.01–1.24) | 0.066 |
| Blood product associated with TT malaria | ||||
| Packed RBCs | 7 (87.5) | 31 (86.1) | – | 1 |
| Whole blood | 1 (12.5) | 4 (11.1) | 0.90 (0.09–9.37) | 0.932 |
| Platelets | 0 (0.0) | 1 (2.8) | 0.71 (0.03–19.33) | 0.842 |
| Plasmodium species | ||||
| Plasmodium falciparum | 9 (50.0) | 39 (12.4) | – | 1 |
| Plasmodium malariae | 7 (38.9) | 204 (65.0) | 6.72 (2.36–19.13) | <0.001 |
| Plasmodium vivax | 2 (11.1) | 63 (20.1) | 7.26 (1.49–35.41) | 0.014 |
| Plasmodium ovale | 0 (0.0) | 7 (2.2) | 3.61 (0.19–68.86) | 0.394 |
| Mixed P. falciparum–P. vivax | 0 (0.0) | 1 (0.3) | 0.72 (0.03–19.14) | 0.845 |
| Incubation period (weeks) | ||||
| ≤4 | 16 (89.9) | 75 (69.4) | – | 1 |
| >4 | 2 (11.1) | 33 (30.6) | 3.52 (0.77–16.19) | 0.106 |