FIG. 7.

Effect of Antcin H on 3-NT generation and MKK4 activation. (A) Western blotting of mitochondrial 3-NT. (B) Immunohistochemical staining for 3-NT after APAP treatment in vivo with or without Antcin H. Representative of n = 3. (C) Immunoblotting of p-MKK4 in liver homogenate from Figure 3C. (D) Cytoplasmic and mitochondrial p-MKK4 were detected by Western blot in samples from Figure 3E. To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars