Table 1.

Plasma Half-Lives (t_1/2) of sbC-Pegylated and Pegylated Aptamers in Mice

	PEG
Aptamers	Product name	MW (kDa)	No. of arms	t1/2 (h)
sbC-PEGylated 17M-200-S1	Y-shaped PEG+Y-shaped PEG	80 (40 + 40)	4 (2 + 2)	22.5
PEGylated 17M-200-S1	SUNBRIGHT® GL4-800GS2	80	4	10.5
	SUNBRIGHT GL2-800GS2	80	2	7.5
	SUNBRIGHT GL4-400GS2	40	4	5.0
	SUNBRIGHT GL2-400GS2	40	2	4.3
	Y-shaped PEG	40	2	3.7
sbC-PEGylated 17M-382	Y-shaped PEG+Y-shaped PEG	80 (40 + 40)	4 (2 + 2)	22.8
	SUNBRIGHT ME-400GS+SUNBRIGHT ME-400GS	80 (40 + 40)	2 (linear+linear)	4.9
PEGylated 17M-382	SUNBRIGHT GL4-800GS2	80	4	20.9

SUNBRIGHT^® is a registered trademark of the NOF Corporation.

MW, molecular weight.