Table 1.

Summary of Simulation Parameters^a

Parameters	Values
IPD-Meta-analyses generated:	M = 1000
(Number of studies, number of subjects per study, total average sample sizes)b:	(K, n i, N) ∈ {(5,100,500), (15,33,500), (15,200,3000), (5,357,500), (15,98,500), (15,588,3000)}
Fixed effects (intercepts):	β 0 = − 0.85
Prevalence of the outcome	π = 30%
Fixed effects (Slopes):	β 1 = 0.18
Random effects distribution:	Normal
Random effects variances:	{τ 20, τ 21} ∈ (0.05, 1, 4)
Correlation between random effects:	ρ ∈ (0,0.5)

^aIn a sensitivity analysis, we extended the number of studies to 50 with an average sample size of 9000 and reduced the prevalence of the outcome to 5%. The prevalence of the outcome was fixed to 30% by setting the value of the intercept β ₀ to –0.85

^bThe number of subjects per study was reported for only large studies when data sets were generated with imbalanced study sizes (bold text: 25% large studies-10 times more subjects)