Table 3.
Association between NHL and quartiles of measured body burden of six PCB congeners, specified PCB functional groups, HCB and DDE
| Exposure | Quartile | n. Ca | n. Co | OR | 95% CI | P-value | p for trend | OR(adj) | 95% CI | P-value | p for trend |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PCB118 | Q1 (8.46, 94.05) | 80 | 68 | 1 | 1 | ||||||
| Q2 (94.25, 148.04) | 68 | 67 | 0.76 | (0.44,1.32) | 0.332 | 0.57 | (0.31,1.08) | 0.084 | |||
| Q3 (148.37, 219.85) | 42 | 66 | 0.45 | (0.24,0.84) | 0.012* | 0.35 | (0.17,0.72) | 0.004* | |||
| Q4 (219.91, 901.63) | 80 | 67 | 0.96 | (0.49,1.87) | 0.909 | 0.571 | 0.67 | (0.3,1.49) | 0.332 | 0.168 | |
| PCB138 | Q1 (10.97, 396.03) | 86 | 67 | 1 | 1 | ||||||
| Q2 (399.73, 562.09) | 60 | 67 | 0.67 | (0.41,1.08) | 0.102 | 0.53 | (0.31,0.91) | 0.021* | |||
| Q3 (562.64, 778.15) | 63 | 67 | 0.63 | (0.37,1.1) | 0.104 | 0.50 | (0.27,0.94) | 0.031* | |||
| Q4 (778.44, 2675.35) | 61 | 67 | 0.60 | (0.33,1.08) | 0.089 | 0.093 | 0.38 | (0.18,0.78) | 0.009* | 0.010* | |
| PCB153 | Q1 (32.47, 812.10) | 88 | 68 | 1 | 1 | ||||||
| Q2 (813.60, 1083.97) | 59 | 66 | 0.60 | (0.36,1.03) | 0.064 | 0.56 | (0.31,1.02) | 0.058 | |||
| Q3 (1088.49, 1489.97) | 60 | 67 | 0.54 | (0.3,0.98) | 0.044* | 0.47 | (0.24,0.93) | 0.031* | |||
| Q4 (1493.70, 4334.12) | 63 | 67 | 0.55 | (0.3,1.04) | 0.066 | 0.078 | 0.37 | (0.17,0.78) | 0.009* | 0.011* | |
| PCB156 | Q1 (15.50, 69.69.62) | 75 | 67 | 1 | 1 | ||||||
| Q2 (69.95, 95.44) | 71 | 67 | 0.88 | (0.49,1.56) | 0.654 | 0.9 | (0.48,1.71) | 0.754 | |||
| Q3 (95.76, 126.68) | 51 | 67 | 0.59 | (0.31,1.11) | 0.100 | 0.56 | (0.27,1.16) | 0.118 | |||
| Q4 (126.87, 394.89) | 73 | 67 | 0.86 | (0.45,1.64) | 0.644 | 0.545 | 0.69 | (0.33,1.45) | 0.326 | 0.228 | |
| PCB170 | Q1 (50.39, 257.50) | 73 | 67 | 1 | 1 | ||||||
| Q2 (257.62, 358.81) | 82 | 68 | 0.99 | (0.59,1.66) | 0.967 | 0.9 | (0.51,1.6) | 0.718 | |||
| Q3 (359.10, 468.52) | 43 | 66 | 0.48 | (0.25,0.92) | 0.028* | 0.37 | (0.17,0.79) | 0.010* | |||
| Q4 (468.55, 1291.23) | 72 | 67 | 0.83 | (0.45,1.53) | 0.55 | 0.356 | 0.59 | (0.28,1.23) | 0.160 | 0.091 | |
| PCB180 | Q1 (100.08, 533.51) | 72 | 67 | 1 | 1 | ||||||
| Q2 (533.84, 730.03) | 78 | 68 | 1.03 | (0.61,1.73) | 0.926 | 1 | (0.55,1.81) | 0.999 | |||
| Q3 (730.81, 966.02) | 46 | 66 | 0.57 | (0.31,1.05) | 0.071 | 0.45 | (0.21,0.95) | 0.035* | |||
| Q4 (966.55, 2708,83) | 74 | 67 | 0.94 | (0.52,1.69) | 0.827 | 0.595 | 0.68 | (0.32,1.42) | 0.300 | 0.168 | |
| HCB | Q1 (62.47, 181.87) | 85 | 67 | 1 | 1 | ||||||
| Q2 (184.78, 288.81) | 62 | 67 | 0.58 | (0.32,1.03) | 0.064 | 0.52 | (0.27,1.02) | 0.057 | |||
| Q3 (289.49, 474.86) | 59 | 67 | 0.47 | (0.24,0.94) | 0.032* | 0.28 | (0.12,0.65) | 0.003* | |||
| Q4 (477.00, 3882.19) | 64 | 66 | 0.49 | (0.22,1.07) | 0.074 | 0.061 | 0.35 | (0.14,0.87) | 0.023* | 0.014* | |
| DDE | Q1 (16.40, 1308.26) | 81 | 67 | 1 | 1 | ||||||
| Q2 (1310.23, 2666.60) | 62 | 67 | 0.65 | (0.37,1.14) | 0.137 | 0.55 | (0.28,1.05) | 0.07 | |||
| Q3 (2675.27, 5523.58) | 68 | 68 | 0.67 | (0.37,1.21) | 0.186 | 0.40 | (0.20,0.84) | 0.015* | |||
| Q4 (5528.29, 30992.76) | 59 | 66 | 0.55 | (0.28,1.08) | 0.082 | 0.106 | 0.34 | (0.15,0.77) | 0.010* | 0.008* |
OR – conditional logistic regression accounting for matching factors
OR(adj) – conditional logistic regression additionally adjusting for BMI, height, educational level, vegetables, dairy, protein, total fat, alcohol
*Significant at the 95% confidence level