Table 5.
Association between log-transformed body burden of six PCB congeners, specified PCB functional groups, HCB and DDE, levels and NHL risk stratified by Subtype
| Exposure | CLL (n = 42) | DLBCL (n = 45) | ||||||||||
| OR | 95% CI | p-value | OR(adj) | 95% CI | p-value | OR | 95% CI | p-value | OR(adj) | 95% CI | p-value | |
| PCB118 | 0.70 | (0.31,1.58) | 0.398 | 5.14 | (0.56,47.08) | 0.147 | 0.74 | (0.27,2.04) | 0.561 | 0.39 | (0.06,2.68) | 0.335 |
| PCB138 | 0.63 | (0.26,1.54) | 0.309 | 1.33 | (0.15,11.91) | 0.801 | 0.37 | (0.10,1.32) | 0.126 | 0.33 | (0.04,2.47) | 0.281 |
| PCB153 | 0.50 | (0.16,1.52) | 0.221 | 0.70 | (0.06,7.77) | 0.772 | 0.32 | (0.08,1.26) | 0.103 | 0.16 | (0.01,1.84) | 0.140 |
| PCB156 | 0.57 | (0.16,2.10) | 0.402 | 1.47 | (0.11,19.75) | 0.773 | 0.25 | (0.06,0.96) | 0.044* | 0.01 | (0,0.53) | 0.023* |
| PCB170 | 0.52 | (0.16,1.66) | 0.267 | 0.34 | (0.03,3.61) | 0.372 | 0.24 | (0.06,1.02) | 0.053 | 0.01 | (0,0.47) | 0.021* |
| PCB180 | 0.49 | (0.14,1.77) | 0.278 | 0.27 | (0.02,4.15) | 0.351 | 0.23 | (0.05,0.97) | 0.045* | 0.01 | (0,0.50) | 0.020* |
| HCB | 0.42 | (0.14,1.26) | 0.121 | 1.12 | (0.17,7.40) | 0.905 | 0.90 | (0.34,2.39) | 0.834 | 0.41 | (0.08,2.00) | 0.271 |
| DDE | 0.83 | (0.44,1.58) | 0.578 | 1.99 | (0.52,7.59) | 0.313 | 0.88 | (0.43,1.84) | 0.743 | 1.17 | (0.35,3.97) | 0.796 |
| Exposure | FL (n = 39) | MM (n = 76) | ||||||||||
| OR | 95% CI | p-value | ORb(adj) | 95% CI | p-value | OR | 95% CI | p-value | ORb(adj) | 95% CI | p-value | |
| PCB118 | 0.95 | (0.41,2.21) | 0.904 | 1.04 | (0.34,3.13) | 0.947 | 1.06 | (0.55,2.07) | 0.856 | 0.62 | (0.23,1.63) | 0.330 |
| PCB138 | 0.91 | (0.31,2.67) | 0.865 | 1.17 | (0.29,4.77) | 0.822 | 0.74 | (0.32,1.70) | 0.474 | 0.45 | (0.15,1.32) | 0.145 |
| PCB153 | 0.94 | (0.29,3.04) | 0.918 | 1.20 | (0.27,5.31) | 0.814 | 0.73 | (0.29,1.85) | 0.512 | 0.41 | (0.12,1.42) | 0.159 |
| PCB156 | 0.99 | (0.32,3.01) | 0.979 | 1.12 | (0.24,5.36) | 0.885 | 0.77 | (0.31,1.88) | 0.561 | 0.47 | (0.14,1.62) | 0.234 |
| PCB170 | 1.39 | (0.43,4.51) | 0.580 | 1.65 | (0.33,8.24) | 0.540 | 0.77 | (0.30,2.00) | 0.588 | 0.42 | (0.11,1.66) | 0.216 |
| PCB180 | 1.43 | (0.44,4.63) | 0.553 | 1.52 | (0.31,7.41) | 0.605 | 0.90 | (0.35,2.31) | 0.834 | 0.56 | (0.15,2.10) | 0.392 |
| HCB | 0.82 | (0.36,1.86) | 0.633 | 0.83 | (0.25,2.70) | 0.752 | 0.70 | (0.30,1.61) | 0.394 | 0.31 | (0.08,1.19) | 0.089 |
| DDE | 0.77 | (0.41,1.48) | 0.437 | 0.93 | (0.34,2.55) | 0.885 | 0.66 | (0.37,1.15) | 0.142 | 0.52 | (0.25,1.10) | 0.086 |
Results for the four largest subtype groups were included
OR – conditional logistic regression accounting for matching factors
OR(adj) – conditional logistic regression additionally adjusting for BMI, height, educational level, vegetables, dairy, protein, total fat, alcohol
*Significant at the 95% confidence level; Matched case-control pairs with incomplete information on potential confounders were excluded from the adjusted analyses