Table 6.
Association between exposure and risk in ‘highly exposed’ individuals high exposure is defined as exposure levels above the 90th of the control exposure distribution, the odds of disease are compared with those in the lowest quartile of exposure
Exposure | 90th percentile control exposure distribution | n cases (%) above 90th percentile | n controls(%) above 90th percentile | OR | 95% CI | p-value | OR(adj) | 95% CI | p-value |
---|---|---|---|---|---|---|---|---|---|
PCB118 | 316.2 | 35(13.0) | 28(10.4) | 1.37 | (0.76,2.45) | 0.294 | 1.25 | (0.65,2.41) | 0.500 |
PCB138 | 1112.4 | 25(9.3) | 29(10.7) | 0.83 | (0.45,1.52) | 0.550 | 0.81 | (0.40,1.64) | 0.562 |
PCB153 | 1965.7 | 29(10.7) | 29(10.7) | 1.01 | (0.56,1.81) | 0.987 | 1.15 | (0.58,2.26) | 0.693 |
PCB156 | 176.4 | 23(8.5) | 28(10.4) | 0.79 | (0.43,1.45) | 0.447 | 0.89 | (0.43,1.81) | 0.739 |
PCB170 | 626.6 | 29(10.7) | 29(10.7) | 1.00 | (0.57,1.78) | 0.989 | 1.07 | (0.55,2.06) | 0.843 |
PCB180 | 1323.3 | 29(10.7) | 28(10.4) | 1.05 | (0.58,1.88) | 0.872 | 1.11 | (0.57,2.14) | 0.763 |
HCB | 872.8 | 25(9.3) | 29(10.7) | 0.80 | (0.41,1.55) | 0.506 | 0.84 | (0.42,1.68) | 0.624 |
DDE | 9787.7 | 27(10) | 28(10.4) | 0.95 | (0.50,1.80) | 0.878 | 1.01 | (0.52,1.97) | 0.978 |
OR – conditional logistic regression accounting for matching factors
OR(adj) – conditional logistic regression additionally adjusting for BMI, height, educational level, vegetables, dairy, protein, total fat, alcohol
Matched case-control pairs with incomplete information on potential confounders were excluded from the adjusted analyses