Table 4.
N | Observation | β | Lower 95% CI | Upper 95% CI | p-Value | |||
---|---|---|---|---|---|---|---|---|
Total | 517 | 1528 | 0.18 | 0.14 | 0.23 | <.0001 | ||
Male | 134 | 365 | 0.19 | 0.09 | 0.29 | 0.0003 | ||
Female | 383 | 1163 | 0.18 | 0.12 | 0.23 | <.0001 | ||
COX2 | rs5277 | GG | 468 | 1392 | 0.17 | 0.12 | 0.22 | <.0001 |
GC | 47 | 131 | 0.26 | 0.13 | 0.38 | 0.0001 | ||
CC | 1 | 3 | - | - | - | - | ||
GC + CC | 48 | 134 | 0.26 | 0.13 | 0.38 | 0.0001 | ||
rs3218625 | GG | 500 | 1480 | 0.18 | 0.14 | 0.23 | <.0001 | |
GA | 17 | 48 | 0.19 | −0.04 | 0.42 | 0.1031 | ||
AA | 0 | 0 | - | - | - | - | ||
GA + AA | 17 | 48 | 0.19 | −0.04 | 0.42 | 0.1031 | ||
EPHX1 | rs3766934 | GG | 329 | 996 | 0.17 | 0.12 | 0.23 | <.0001 |
GT | 164 | 472 | 0.20 | 0.11 | 0.29 | <.0001 | ||
TT | 22 | 53 | 0.22 | −0.02 | 0.46 | 0.0667 | ||
GT + TT | 186 | 525 | 0.20 | 0.12 | 0.28 | <.0001 | ||
rs1051740 | TT | 172 | 501 | 0.16 | 0.08 | 0.24 | 0.0001 | |
TC | 258 | 768 | 0.19 | 0.12 | 0.25 | <.0001 | ||
CC | 83 | 250 | 0.22 | 0.10 | 0.33 | 0.0003 | ||
rs2234922 | AA | 380 | 1129 | 0.18 | 0.13 | 0.24 | <.0001 | |
AG | 125 | 365 | 0.20 | 0.12 | 0.29 | <.0001 | ||
GG | 4 | 12 | 0.93 | −3.41 | 5.27 | 0.4539 | ||
AG + GG | 129 | 377 | 0.20 | 0.12 | 0.29 | <.0001 | ||
HSP70-hom | rs2227956 | TT | 408 | 1202 | 0.18 | 0.13 | 0.23 | <.0001 |
TC | 103 | 310 | 0.18 | 0.05 | 0.31 | 0.0084 | ||
CC | 1 | 2 | - | - | - | - | ||
TC + CC | 104 | 312 | 0.18 | 0.05 | 0.31 | 0.0061 | ||
rs2075800 | GG | 181 | 541 | 0.20 | 0.12 | 0.28 | <.0001 | |
GA | 242 | 718 | 0.14 | 0.07 | 0.21 | <.0001 | ||
AA | 91 | 261 | 0.22 | 0.12 | 0.33 | <.0001 | ||
PON1 | rs854560 | TT | 455 | 1342 | 0.19 | 0.14 | 0.23 | <.0001 |
TA | 57 | 174 | 0.13 | −0.02 | 0.28 | 0.0783 | ||
AA | 2 | 4 | - | - | - | - | ||
TA + AA | 59 | 178 | 0.14 | −0.01 | 0.29 | 0.0669 | ||
rs13306698 | AA | 451 | 1328 | 0.19 | 0.15 | 0.24 | <.0001 | |
AG | 62 | 187 | 0.17 | −0.01 | 0.35 | 0.0687 | ||
GG | 3 | 9 | - | - | - | - | ||
AG + GG | 65 | 196 | 0.16 | −0.01 | 0.34 | 0.0662 | ||
rs662 | GG | 211 | 636 | 0.16 | 0.09 | 0.23 | <.0001 | |
GA | 209 | 597 | 0.20 | 0.11 | 0.28 | <.0001 | ||
AA | 64 | 193 | 0.24 | 0.13 | 0.36 | <.0001 | ||
eNOS | rs1799983 | GG | 441 | 1309 | 0.18 | 0.13 | 0.23 | <.0001 |
GT | 71 | 206 | 0.15 | 0.01 | 0.28 | 0.0308 | ||
TT | 2 | 7 | - | - | - | - | ||
GT + TT | 73 | 213 | 0.15 | 0.01 | 0.28 | 0.0299 | ||
rs2853796 | TT | 202 | 589 | 0.20 | 0.13 | 0.27 | <.0001 | |
TG | 241 | 720 | 0.17 | 0.10 | 0.24 | <.0001 | ||
GG | 71 | 210 | 0.15 | 0.02 | 0.28 | 0.0247 | ||
rs7830 | GG | 158 | 453 | 0.23 | 0.14 | 0.31 | <.0001 | |
GT | 252 | 741 | 0.17 | 0.10 | 0.25 | <.0001 | ||
TT | 105 | 327 | 0.16 | 0.08 | 0.25 | 0.0001 | ||
CAT | rs769218 | GG | 171 | 484 | 0.14 | 0.05 | 0.22 | 0.0016 |
GA | 259 | 787 | 0.19 | 0.13 | 0.25 | <.0001 | ||
AA | 86 | 256 | 0.26 | 0.13 | 0.38 | <.0001 | ||
rs769217 | CC | 172 | 485 | 0.14 | 0.05 | 0.22 | 0.0016 | |
CT | 254 | 772 | 0.19 | 0.13 | 0.26 | <.0001 | ||
TT | 82 | 246 | 0.25 | 0.12 | 0.38 | 0.0002 | ||
DRD2 | rs1800497 | GG | 197 | 583 | 0.19 | 0.11 | 0.26 | <.0001 |
GA | 232 | 679 | 0.20 | 0.13 | 0.26 | <.0001 | ||
AA | 86 | 259 | 0.15 | 0.02 | 0.28 | 0.0276 | ||
SOD2 | rs4880 | TT | 400 | 1189 | 0.20 | 0.14 | 0.25 | <.0001 |
TC | 106 | 306 | 0.12 | 0.00 | 0.23 | 0.0430 | ||
CC | 6 | 20 | 0.66 | −0.04 | 1.35 | 0.0624 | ||
TC + CC | 112 | 326 | 0.15 | 0.04 | 0.26 | 0.0074 | ||
rs2758331 | GG | 406 | 1204 | 0.20 | 0.14 | 0.25 | <.0001 | |
GT | 103 | 299 | 0.12 | 0.00 | 0.23 | 0.0500 | ||
TT | 5 | 17 | 0.64 | −0.29 | 1.56 | 0.1438 | ||
GT + TT | 108 | 316 | 0.15 | 0.04 | 0.26 | 0.0094 | ||
rs5746136 | GG | 167 | 520 | 0.17 | 0.09 | 0.26 | <.0001 | |
GA | 260 | 750 | 0.16 | 0.09 | 0.22 | <.0001 | ||
AA | 88 | 255 | 0.25 | 0.14 | 0.35 | <.0001 | ||
MPO | rs7208693 | GG | 408 | 1199 | 0.19 | 0.14 | 0.24 | <.0001 |
GT | 97 | 293 | 0.16 | 0.03 | 0.29 | 0.0197 | ||
TT | 8 | 24 | - | - | - | - | ||
GT + TT | 105 | 317 | 0.15 | 0.02 | 0.27 | 0.0224 | ||
rs2071409 | AA | 442 | 1300 | 0.19 | 0.13 | 0.24 | <.0001 | |
AC | 70 | 214 | 0.17 | 0.06 | 0.27 | 0.0016 | ||
CC | 2 | 5 | - | - | - | - | ||
AC + CC | 72 | 219 | 0.17 | 0.07 | 0.27 | 0.0011 |
Adjusted for age, sex, BMI, drinking status, exercise, urinary cotinine level, PM10 on lag day 2, and mean temperature and dew point on the day