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AAV delivery attenuated cold-induced cardiac hypertrophy. (A) Heart weight. (B) LV:heart weight ratio. (C) Myocyte area. (D) Kidney weight. These parameters were measured at 10 weeks after exposure to cold. Data shown as means ± SEM; n = 8. **p < 0.01, ***p < 0.001 vs. warm-PBS group. +p < 0.05, ++p < 0.01 vs. the cold-SC-shRNA group.
