Fig. 3.

Effect of EETC on DPB-induced molecules involve in inflammation and tissue damage. a Inflammatory cytokine modulated by DPB-LPS and EETC in gingival epithelial cell. Analysis of culture medium (CM) collected from DMSO-treated cells, which served as the control. Altered factors are indicated with rectangles and circled numbers. The list altered factor is shown as fold-change in the graph. The data shown are representative of three independent experiments. *P < 0.01 vs. DPB1^#-LPS-treated medium, ^# P < 0.001 vs. DMSO control medium. b Protease modulated by DPB-LPS and EETC in gingival epithelial cell. Altered factors are indicated with rectangles and circled numbers. The list altered factor is depicted in the graph and is shown as fold-change. The data shown are representative of three independent experiments. *P < 0.01 vs. DPB1^#-LPS-treated medium, ^# P < 0.001 vs. DMSO control medium. c Effect of tissue damage by DPB-LPS and/or EETC on FITC-conjugated gelatin matrix-coated coverslips. The data shown are representative of five independent experiments