The ratio of signal variance before and after WB-LNR (top, averaged across all the brain functional ROIs when tested against 0 using one-sample t-test, all passing the significance level p < 0.0001, Bonferroni corrected); an example of variance changes in different brain networks, postregression using mot24 + comb (bottom, averaged across ROIs within different RS networks). ROIs, regions of interest; RS, resting state. Color images available online at www.liebertpub.com/brain