FIG. 2.

Small RNA-seq of Dgcr8^+/− and Dgcr8^−/− NSCs. (A) Percentage miRNA reads in total small RNA-seq reads of Dgcr8^+/− and Dgcr8^−/− NSCs. (B) Heatmap of miRNA expression in Dgcr8^+/− and Dgcr8^−/− NSCs. (C) Percentage noncanonical miRNA reads (Dgcr8-independent) in total miRNA reads of Dgcr8^+/− and Dgcr8^−/− NSCs. (D) Heatmaps of mature miRNAs (left) and corresponding pri-miRNAs (right) in Dgcr8^+/− and Dgcr8^−/− NSCs. Shown are those miRNAs with differential expression of corresponding pri-miRNA (>2-fold, P < 0.01) in mRNA-seq analysis of Dgcr8^+/− and Dgcr8^−/− NSCs. (E) Pie graph of the most abundantly expressed miRNAs in Dgcr8^+/− NSCs. (F) Pie graph of the most abundantly expressed miRNAs in Dgcr8^−/− NSCs. Color images available online at www.liebertpub.com/scd