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Bioconjugation strategies for targeted CPSNPs. A. Schematic of the steps used to bioconjugate either G16 peptide or AP1153 to the surface of CPSNPSs. After activation of the nanoparticle surface with PEG derivatives, functionalization with either AP1153 or G16 peptide was done as outlined. CPSNP, calcium phosphosilicate nanoparticle; G16, gastrin 16.
