Fig 4. Inhibition of the hemorrhagic activity of B. jararaca (BiV) venom by extracts of K. brasiliensis (Kb) (A) and K pinnata (Kp) (B) in post-treatment protocol.

BjV was injected s.c. in the ventral region of 5 mice before treatement with extract (500 mg/kg, i.p.). Three hours after venom injection, the skin was removed and weighed. The columns represent the mean ± SEM (n = 5). ***p<0.001 compared to venom alone (one-way ANOVA followed by the Tukey’s test).