Male St6gal1 knockout mice gained more body weight and VAT weight from HFD feeding than littermate heterozygous mice.
A, levels of serum biochemical markers after 8 weeks of HFD feeding. B, change in bodyweight of male mice fed a control diet for 4 weeks and subsequently fed an HFD for 8 weeks. C, weight of VATs after 8 weeks of HFD feeding. D, mRNA expression of the Ki67 gene in VATs. All graphs show mean ± S.E. (*, p < 0.05 versus St6gal1+/− by Mann-Whitney U test; #, p < 0.05 by Student's t test).