TABLE 1.

HDAC inhibitors used in this work

HDACs	Inhibitor	IC50	Refs.
HDAC1	CAS 193551-00-7	100 (HDAC1); >1,000 nm (HDAC3)	23, 25
HDAC3	Apicidin	8 nm (HDAC3); 120 nm (HDAC 2); > 10,000 nm (HDACs 1, 4, 6, 7, and 9)	22, 33, 34
HDACs 1 and 2	Romidepsin	36 nm (HDAC1); 47 nm (HDAC2); 510 nm (HDAC4); >10,000 nm (HDAC6)	26–28
HDACs 1, 2, 3, and 9	Entinostat (MS-275)	181 nm (HDAC1); 1100 nm (HDAC2); 2300 nm (HDAC3); 505 nm (HDAC9); >10,000 nm (HDACs 4, 6, 7, and 8)	22, 35–37
Class IIa	MC-1568	220 nm (HDACs 4, 5, 7, and 9)	29, 38, 39
Global	Sodium butyrate	0.8 mm	20, 21, 40, 41