Skip to main content
. 2017 Feb 16;12(2):e0171898. doi: 10.1371/journal.pone.0171898

Fig 6. 4-MU inhibits larval tail regeneration.

Fig 6

(A) Representative micrographs of larval tails that were amputated at 2 dpf and then treated 0.5% DMSO or 150 μM 4-MU for 3 days. Dotted lines indicate the amputation plane, and micrographs of uncut larval tails subjected to the same inhibitor regimen are shown for comparison. Scale bar: 100 μm. (B-C) Time-course analysis of 4-MU action on larval tail regeneration. Caudal fin sizes at 5 dpf (3 dpa) after the indicated amputation and 4-MU treatment regimens. Data are the average caudal fin areas of 15 larvae ± s.e.m., normalized to the average fin size of uncut larvae treated with 0.5% DMSO. ***, P < 0.001.