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. 2017 Feb 16;12(2):e0171898. doi: 10.1371/journal.pone.0171898

Fig 8. 4-MU inhibits regenerative cell proliferation.

Fig 8

(A) Mitotic cells in the larval tail after the indicated amputation and 4-MU treatment regimens, as visualized with anti-pH3 immunostaining at 2 dpa (4 dpf). R1 and R2 demarcate distinct regions within the larval tail, with R1 corresponding to a highly proliferative 100-μm-wide zone associated with tail regeneration. (B) Quantification of pH3-positive cells in the R1 and R2 regions under the indicated treatment conditions. Data are the average number of pH3-positive cells in 30 larval tails ± s.e.m. **, P < 0.01.