Fig 14. GED markedly increased the GSK-3β phosphorylation in DSS-induced chronic colitis in mice.
(A) Western blot analysis of phospho-GSK-3β and GSK-3β protein levels on three of the five mice groups (H2O, DSS, DSS+GED). Vinculin was used as internal loading control. (B) Densitometric analysis of GSK-3β phosphorylation (phospho-GSK-3β/GSK-3β ratio). A strong (p = 0.0006) GSK-3β phosphorylation was observed in the GED group compared to the H20 and DSS groups, whereas there were not significant modulations between the latter two groups. Data are presented as mean of fold changes vs CTRL.