Table 1. Fraction of near-native protein-protein geometries obtained for the pdb2oo9-homodimer in RP-REMD-DOCK and MD simulations.
fraction of near native solutions in reference replica | ||
---|---|---|
Start struct. (RMSDlig >25 Å | 0–10 ns RMSDlig<2 Å (<4 Å) | 10–20 ns RMSDlig<2 Å (<4 Å) |
RP-REMD-DOCK 1 (2) | 0.10 (0.43) | 0.15 (0.55) |
RP-REMD-DOCK 2 (3) | 0.06 (0.21) | 0.10 (0.28) |
RP-REMD-DOCK 3 (5) | 0.07 (0.25) | 0.20 (0.64) |
RP-REMD-DOCK 4 (6) | 0.08 (0.23) | 0.11(0.34) |
RP-REMD-DOCK 5 (7) | 0.18 (0.48) | 0.24 (0.87) |
MD-1 (10 x 20 ns) (3) | 0.00 (0.00) | 0.00 (0.02) |
MD-2 (10 x 20 ns) (6) | 0.03 (0.09) | 0.04 (0.10) |