Table 3. Risk factor analysis of osteoporosis in patients with atopic dermatitis.

Variables	Adjusted HR a	(95% CI)b	P-value
Age (years)	2.02	(1.84–2.20)	<0.001
Female gender	3.91	(2.92–5.23)	<0.001
Charlson Comorbidity Index	1.73	(1.52–1.95)	<0.001
Depression	1.50	(1.18–1.89)	<0.001
Systemic corticosteroids use	1.42	(1.14–1.76)	0.001

^aHR, hazard ratio; adjusted HR, adjusted for age, sex, comorbidities (hypertension, diabetes mellitus, hyperlipidaemia, chronic kidney disease, chronic liver disease, chronic obstructive pulmonary disease, depression) and use of systemic corticosteroids.

^b 95% CI,95% confidence interval.

The adjusted HR and 95% CI were estimated by a stepwise the Cox proportional hazards regression method.