Table 3. Linear regression analysis of variables associated with CTRP1 (n = 262).
Simple | Multiple | |||
---|---|---|---|---|
Variable | r | P | β | P |
Age (year) | 0.140 | 0.024 | 0.118 | 0.043 |
BMI (kg/m2) | 0.021 | 0.731 | ||
SBP (mm Hg) | 0.271 | < 0.010 | -0.061 | 0.454 |
DBP (mm Hg) | 0.311 | < 0.010 | 0.188 | 0.021 |
TCH (mmol/L) | 0.173 | < 0.010 | 0.006 | 0.972 |
HDL-cholesterol (mmol/L) | -0.075 | 0.227 | ||
LDL-cholesterol (mmol/L) | 0.129 | 0.037 | -0.104 | 0.192 |
VLDL-cholesterol (mmol/L) | 0.012 | 0.841 | ||
Triglycerides (mmol/L) | 0.287 | < 0.010 | 0.440 | 0.294 |
TCH/HDL | 0.223 | < 0.010 | 0.119 | 0.333 |
TG/HDL | 0.244 | < 0.010 | -0.317 | 0.416 |
Glucose (mmol/L) | 0.596 | < 0.010 | 0.456 | < 0.010 |
Insulin (pmol/L) | 0.125 | 0.044 | 0.376 | 0.082 |
HOMA-IR | 0.411 | < 0.010 | -0.414 | 0.080 |
CRP (mg/l) | 0.382 | < 0.010 | 0.077 | 0.186 |
Endothelial lipase (ng/ml) | 0.092 | 0.138 | ||
Leptin (ng/ml) | -0.148 | 0.017 | -0.094 | 0.086 |
Adiponectin (μg/ml) | -0.230 | < 0.010 | -0.024 | 0.664 |
CTRP9 (ng/ml) | 0.084 | 0.176 | ||
CTRP12 (pg/ml) | -0.383 | < 0.010 | -0.153 | < 0.010 |
CTRP13 (ng/ml) | 0.026 | 0.673 |
Spearman Rank correlation was used for calculation of associations between variables. If individual bivariate correlations achieved statistical significance, multiple regression analysis with CTRP1 was performed to test the joint effect of these parameters on CTRP1. BMI = body mass index; SBP = systolic blood pressure; DBP = diastolic blood pressure; TCH = total cholesterol; HDL = High-density lipoprotein; LDL = Low-density lipoprotein; VLDL = Very low-density lipoprotein; TG = triglycerides; HOMA-IR = homeostatic model assessment–insulin resistance; CRP = C-reactive protein; CTRP = C1q complement/TNF-related protein; NS = not significant.