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. 2017 Feb 16;12(2):e0172271. doi: 10.1371/journal.pone.0172271

Table 3. Linear regression analysis of variables associated with CTRP1 (n = 262).

Simple Multiple
Variable r P β P
Age (year) 0.140 0.024 0.118 0.043
BMI (kg/m2) 0.021 0.731
SBP (mm Hg) 0.271 < 0.010 -0.061 0.454
DBP (mm Hg) 0.311 < 0.010 0.188 0.021
TCH (mmol/L) 0.173 < 0.010 0.006 0.972
HDL-cholesterol (mmol/L) -0.075 0.227
LDL-cholesterol (mmol/L) 0.129 0.037 -0.104 0.192
VLDL-cholesterol (mmol/L) 0.012 0.841
Triglycerides (mmol/L) 0.287 < 0.010 0.440 0.294
TCH/HDL 0.223 < 0.010 0.119 0.333
TG/HDL 0.244 < 0.010 -0.317 0.416
Glucose (mmol/L) 0.596 < 0.010 0.456 < 0.010
Insulin (pmol/L) 0.125 0.044 0.376 0.082
HOMA-IR 0.411 < 0.010 -0.414 0.080
CRP (mg/l) 0.382 < 0.010 0.077 0.186
Endothelial lipase (ng/ml) 0.092 0.138
Leptin (ng/ml) -0.148 0.017 -0.094 0.086
Adiponectin (μg/ml) -0.230 < 0.010 -0.024 0.664
CTRP9 (ng/ml) 0.084 0.176
CTRP12 (pg/ml) -0.383 < 0.010 -0.153 < 0.010
CTRP13 (ng/ml) 0.026 0.673

Spearman Rank correlation was used for calculation of associations between variables. If individual bivariate correlations achieved statistical significance, multiple regression analysis with CTRP1 was performed to test the joint effect of these parameters on CTRP1. BMI = body mass index; SBP = systolic blood pressure; DBP = diastolic blood pressure; TCH = total cholesterol; HDL = High-density lipoprotein; LDL = Low-density lipoprotein; VLDL = Very low-density lipoprotein; TG = triglycerides; HOMA-IR = homeostatic model assessment–insulin resistance; CRP = C-reactive protein; CTRP = C1q complement/TNF-related protein; NS = not significant.