Table 1.
Patients characteristics for human bladder cancer tissue microarray
| Clinical characteristic | TMA (All cases) | TMA (Subset w/p53 mutations) | TMA (Subset w/p53 mutations and chemotherapy) |
|---|---|---|---|
|
| |||
| Number of samples # | 190 | 35 | 15 |
|
| |||
| Age at cystectomy (years) | |||
| Median (range) | 69 (38–87) | 71 (43–87) | 67 (43–81) |
|
| |||
| Gender: | |||
| Male | 146 | 26 | 12 |
| Female | 44 | 9 | 3 |
|
| |||
| T stage: | |||
| Ta | 1 | 0 | 0 |
| T1 | 8 | 1 | 0 |
| T2 | 50 | 9 | 3 |
| T3 | 108 | 22 | 10 |
| T4 | 23 | 3 | 2 |
|
| |||
| Lymph node status: | |||
| Negative | 132 | 20 | 10 |
| Positive (not available) | 56 (2) | 15 | 5 |
|
| |||
| Sample tissue type: | |||
| Primary | 186 | 34 | 14 |
| Metastasis | 4 | 1 | 1 |
|
| |||
| Recurrence: | |||
| Yes/No (not available) | 107/77 (6) | 19/16 | 11/4 |
|
| |||
| Vital status: (Dead/Alive) | 105/85 | 17/18 | 9/6 |
|
| |||
| Follow-up in months: | |||
| Median (range) | 26.4 (0.2–168) | 35.1 (1.7–87.2) | 35.1 (4.9–83.9) |
|
| |||
| Expression of ARF: | |||
| Nucleolar | 29 | 12 | 7 |
| Non-Nucleolar or no expression (not available) | 150 (11) | 27 | 8 |
|
| |||
| TP53 mutation or deletion (not available) | 35 of 85 (105) | 35/35 | 15/15 |
|
| |||
| CDKN2A deletion | N/A | N/A | 1/15 |
|
| |||
| Cisplatin containing regimen: | N/A | 15/35 | 15/35 |
| gemcitabine/cisplatin | 9 | ||
| gemcitabine/carboplatin | 3 | ||
| gemcitabine/taxol/carboplatin | 1 | ||
| gemcitabine/taxol/cisplatin | 1 | ||
| etoposide/cisplatin | 1 | ||