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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Kidney Int. 2016 Dec 1;91(3):642–657. doi: 10.1016/j.kint.2016.09.036

Figure 2. Down-regulated pigment epithelium-derived factor (PEDF) and activated Wnt signaling in the kidneys of db/db mice.

Figure 2

(a) Western blot analysis and (b–h) densitometry quantification of PEDF, phosphorylated low-density lipoprotein receptor-related protein 6 (p-LRP6), total LRP6, non-phosphorylated β-catenin (non-p-β-catenin), total β-catenin, connective tissue growth factor (CTGF) and collagen III in kidney homogenates from 6 month-old db/db mice and wild-type (WT) controls (n=10). Each lane represents an individual mouse. &&p<0.01, db/db versus WT. All values are expressed as mean±SD.