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. 2017 Feb 17;8:216. doi: 10.3389/fmicb.2017.00216

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Copyright © 2017 Zheng, Ding, Chen, Yu, Lou, Tong, Kong and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Specific antibody responses induced by DNA immunization with pVAX1-TgSPATR, pVAX1, PBS and blank control, as assessed by ELISA. (A) Determination of specific anti-TgSPATR antibodies in the sera of BALB/c mice. Serum samples were collected at 0, 2, 4, and 6 weeks post-primary immunization. (B) Determination of the specific anti-TgSPATR IgG subclass profile in the sera of immunized BALB/c mice. Results are expressed as means of the OD₄₅₀ value and the standard deviation (n = 10); statistically significant differences (p < 0.05) are indicated by an asterisk (^*).