FIGURE 8.

JDP2 null females have higher levels of FSH and higher expression of Fshb. A and B, serum from six 8-week-old females per genotype was analyzed by a radioimmunoassay for LH and FSH. C–E, whole pituitary mRNA was extracted from 6 animals/group, and mRNA levels for Lhb (C), Fshb (D), and common Cga encoding α-GSU (E) were determined by qPCR. White bars, wild type; black bars, JDP2 nulls. *, significant difference in the JDP2 null animals from the wild type animals; p < 0.05. Error bars, S.E.