TABLE 2.

miRNAs differentially expressed in Treg versus Th1/Th17 cell-derived EVs

Shown are results from ANOVA and Newman-Keuls Multiple comparison post-ANOVA test for miRNAs differentially expressed in Treg versus Th1/Th17 cell-derived EVs. NS, not significant.

miRNA	T cell-derived EV-associated subset specific miRNA signature
	p value ANOVA			Post-ANOVA testing (whole data set)
	Discovery	Validation	Whole data set	Th1 vs. Th17	Th1 vs. Treg	Th17 vs. Treg
miR-106a-5p	0.0335	0.0047	4.62E-05	NS	<0.001	<0.01
miR-155-5p	0.0001	0.0003	1.47E-08	NS	<0.001	<0.001
miR-19a-3p	0.0157	0.0011	2.03E-05	NS	<0.01	<0.001
miR-146a-5p	0.0013	0.00001	2.00E-09	NS	<0.001	<0.001
miR-150-5p	0.0068	0.0011	1.41E-04	NS	<0.001	<0.001
miR-21-5p	0.0074	0.00003	1.07E-05	NS	<0.001	<0.001