TABLE 2.
Association between clinicopathologic factors and CUL4A/CUL4B expression
The boldface italic P values indicate statistical significance.
| Variable | Case no. (%) | CUL4A, case no. (%) |
CUL4B, case no. (%) |
||||
|---|---|---|---|---|---|---|---|
| Low | High | P | Low | High | P | ||
| Age (years) | |||||||
| <60 | 164 (47) | 84 (51) | 80 (49) | 0.599 | 84 (51) | 80 (49) | 0.128 |
| >=60 | 188 (53) | 91 (48) | 97 (52) | 81 (43) | 107 (57) | ||
| Gender | |||||||
| Male | 233 (66) | 116 (49) | 117 (51) | 0.971 | 101 (43) | 132 (57) | 0.064 |
| Female | 119 (34) | 59 (49) | 60 (51) | 64 (54) | 55 (46) | ||
| Smoking | |||||||
| No | 141 (40) | 82 (58) | 59 (42) | 0.010 | 74 (52) | 67 (48) | 0.085 |
| Yes | 211 (60) | 93 (44) | 118(56) | 91 (43) | 120 (57) | ||
| Stage | |||||||
| I | 113 (32) | 71 (63) | 42 (37) | <0.001 | 69 (61) | 44 (39) | <0.001 |
| II | 83 (24) | 47 (57) | 36 (43) | 46 (55) | 37 (45) | ||
| III | 123 (35) | 47 (38) | 76 (62) | 42(34) | 81 (66) | ||
| IV | 33 (09) | 10 (30) | 23 (70) | 8 (24) | 25 (76) | ||
| Tumor size | |||||||
| T1-T2 | 242 (69) | 138 (57) | 104 (43) | <0.001 | 127 (52) | 115 (48) | 0.002 |
| T3-T4 | 110 (31) | 37 (34) | 73 (66) | 38 (35) | 72 (65) | ||
| Lymphatic invasion | |||||||
| Absent | 174 (49) | 100 (57) | 74 (43) | 0.004 | 99 (57) | 75 (43) | <0.001 |
| Present | 178 (51) | 75 (42) | 103 (58) | 66 (37) | 112 (63) | ||
| Metastasis | |||||||
| No | 319 (91) | 165 (52) | 154 (48) | 0.019 | 157 (49) | 162 (51) | 0.006 |
| Yes | 33 (09) | 10 (30) | 23 (70) | 8 (24) | 25 (76) | ||