TABLE 5.
Association between clinicopathologic factors and OS and PFS in lung carcinoma
The boldface italic P values indicate statistical significance.
| Variable | Case no. (%) | OS |
PFS |
||
|---|---|---|---|---|---|
| 5-Year OS (%) | P | 5-Year PFS (%) | P | ||
| Age (years) | |||||
| <60 | 154 (47) | 48.0 | 0.505 | 40.2 | 0.627 |
| >=60 | 173 (53) | 48.1 | 36.4 | ||
| Gender | |||||
| Male | 218 (67) | 49.6 | 0.327 | 36.3 | 0.981 |
| Female | 109 (33) | 46.1 | 40.6 | ||
| Smoking | |||||
| No | 130 (40) | 45.4 | 0.278 | 39.2 | 0.422 |
| Yes | 197 (60) | 50.4 | 35.8 | ||
| Stage | |||||
| I-II | 194 (59) | 62.9 | <0.001 | 50.6 | <0.001 |
| III-IV | 133 (41) | 27.1 | 19.3 | ||
| Tumor size | |||||
| T1-T2 | 250 (76) | 52.0 | 0.016 | 42.9 | <0.001 |
| T3-T4 | 77 (24) | 37.1 | 22.0 | ||
| Lymphatic invasion | |||||
| Absent | 171 (52) | 64.5 | <0.001 | 49.1 | <0.001 |
| Present | 156 (48) | 30.8 | 25.8 | ||
| Metastasis | |||||
| No | 300 (92) | 49.9 | 0.004 | 39.4 | 0.007 |
| Yes | 27 (08) | 32.1 | 19.4 | ||
| CUL4A | |||||
| Low | 163 (49) | 63.2 | <0.001 | 47.6 | <0.001 |
| High | 164 (51) | 33.5 | 28.2 | ||
| CUL4B | |||||
| Low | 157 (48) | 59.4 | <0.001 | 46.3 | 0.001 |
| High | 170 (52) | 38.3 | 30.1 | ||