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. 2016 Dec 14;292(7):2966–2978. doi: 10.1074/jbc.M116.765230

TABLE 5.

Association between clinicopathologic factors and OS and PFS in lung carcinoma

The boldface italic P values indicate statistical significance.

Variable Case no. (%) OS
PFS
5-Year OS (%) P 5-Year PFS (%) P
Age (years)
    <60 154 (47) 48.0 0.505 40.2 0.627
    >=60 173 (53) 48.1 36.4

Gender
    Male 218 (67) 49.6 0.327 36.3 0.981
    Female 109 (33) 46.1 40.6

Smoking
    No 130 (40) 45.4 0.278 39.2 0.422
    Yes 197 (60) 50.4 35.8

Stage
    I-II 194 (59) 62.9 <0.001 50.6 <0.001
    III-IV 133 (41) 27.1 19.3

Tumor size
    T1-T2 250 (76) 52.0 0.016 42.9 <0.001
    T3-T4 77 (24) 37.1 22.0

Lymphatic invasion
    Absent 171 (52) 64.5 <0.001 49.1 <0.001
    Present 156 (48) 30.8 25.8

Metastasis
    No 300 (92) 49.9 0.004 39.4 0.007
    Yes 27 (08) 32.1 19.4

CUL4A
    Low 163 (49) 63.2 <0.001 47.6 <0.001
    High 164 (51) 33.5 28.2

CUL4B
    Low 157 (48) 59.4 <0.001 46.3 0.001
    High 170 (52) 38.3 30.1