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. 2017 Feb 15;9(2):50–61. doi: 10.4251/wjgo.v9.i2.50

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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.

Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Cytology of anal intraepithelial lesions. A: LSIL, with representative binucleate hyperchromatic cells (koilocytes) and nuclear enlargement (Papanicolaou stain, original magnification × 400); B: HSIL, with representative markedly increased nuclear to cytoplasmis ratio as comparted to LSIL at left (Papanicolaou stain, oil immersion, original magnification × 1000). Reproduced with permission[85]. LSIL: Low grade squamous intraepithelial lesions; HSIL: High grade squamous intraepithelial lesions.