Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Histologic examples of high grade anal intraepithelial neoplasia, hematoxylin and eosin stain. A: High grade AIN as demonstrated by nuclear pleomorphism, numerous mitoses and no maturation of the epithelium (original magnification × 400); B: Microinvasion of a high grade AIN demonstrated by a budding off of atypical cells with paradoxical maturation and a marked inflammatory response (original magnification × 200). Reproduced with permission[85]. AIN: Anal intraepithelial neoplasia.
