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. 2017 Feb 17;7:42646. doi: 10.1038/srep42646

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Integrative analyses of the DGE and H3K27ac DHA gene sets at 4 h or 72 h after UVR. Correlations between gene expression and H3K27ac are considered significant if p < 0.05. P-values were obtained using Student’s t-test by comparing the log2FC of the expression values of the genes from the three DHA groups; (B) Representative genes showing concordant changes in gene expression and H3K27ac following UVR. Cutoff is set at Log₂FC > 1 or <−1 for both DGE and DHA; (C) A summary of the overall correlations between DGE and DHA changes among UV-responsive genes at 4 h or 72 h after UVR. Pink highlights positive correlations; green highlights inverse correlations between DGE and DHA; (D) Parallel analysis of H3K27 DHA status of the DGEs that are enriched in top UV-responsive biological pathways.