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. 2017 Feb 17;7:42798. doi: 10.1038/srep42798

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Enzymes previously described in hepatocyte-secreted EVs¹¹ were mapped in the complete map of cellular metabolic pathways by using KEGG Mapper-search & color pathway tool. Enzymes detected in hepatic EVs are highlighted in blue. Cellular pathways that are represented in hepatocyte-secreted EVs are indicated with labels.