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. 2017 Feb 17;7:42979. doi: 10.1038/srep42979

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A,D) Chemotherapy plus bisphosphonates showed similar PFS and OS than chemotherapy alone in patients with NSCLC; (B,E) Chemotherapy plus bisphosphonates showed no superior PFS and OS than chemotherapy alone in NSCLC patients with EGFR mutations and BM; (C,F) Chemotherapy plus bisphosphonates showed no superior PFS and OS than chemotherapy alone in NSCLC patients with EGFR wild type and BM.