Skip to main content
. Author manuscript; available in PMC: 2017 Feb 17.
Published in final edited form as: Am J Psychiatry. 2015 Dec 7;173(4):373–384. doi: 10.1176/appi.ajp.2015.14091200

TABLE 3.

Regional Brain Structure Characteristics of Probands With Psychosis and Their First-Degree Relatives, by Proband DSM Diagnosis and Biotypea

Group Separation From Healthy Subjects, in Effect Size Units
Proband DSM Diagnosisb
 Proband Biotype Class
Group and Brain Region BDP SzAff SZ Biotype1 Biotype2 Biotype3
Probands
Frontal/inferior frontal gyrus 0.54 0.70 0.84 1.0 0.82 0.52
Cingulate gyrus 0.43 0.73 0.68 0.97 0.66 0.52
Temporal/superior temporal gyrus 0.55 0.68 0.76 0.88 0.80 0.53
Occipital/lingual gyrus 0.16 0.64 0.60 0.73 0.65 0.38
Cerebellum 0.00 0.62 0.56 0.72 0.62 0.34
Overall 0.34 0.67 0.69 0.86 0.71 0.46
Relatives
Frontal/inferior frontal gyrus 0.00 0.00 0.16 0.43 0.00 0.16
Cingulate gyrus 0.00 0.21 0.35 0.41 0.00 0.00
Temporal/superior temporal gyrus 0.15 0.23 0.17 0.40 0.00 0.34
Occipital/lingual gyrus 0.00 0.36 0.40 0.41 0.42 0.00
Cerebellum 0.00 0.16 0.32 0.34 0.44 0.00
Overall 0.03 0.19 0.28 0.40 0.17 0.10
a

Brain images showing contrasts with healthy subjects for probands and relatives are provided in Figure 3. In this table, each “Overall” row provides data averaged over all selected brain regions. See Table S8 in the online data supplement for these data for all brain regions.

b

BDP, bipolar disorder with psychosis. SzAff, schizoaffective disorder. SZ, schizophrenia.