Table 1.
Subject Demographic and Clinical Data
| H | SZ | BDP | SZrel | BDPrel | |
|---|---|---|---|---|---|
| Subjects in analyses (# of females) | 225 (131) | 229 (78) | 179 (109) | 255 (171) | 215 (139) |
| Age | 37.40 (12.5) | 35.11 (12.7) | 36.13 (12.8) | 43.52 (15.4) | 40.40 (15.7) |
| HU (# of females) | 53 (30) | 39 (14) | 23 (16) | 39 (27) | 17 (13) |
| UIC (# of females) | 67 (37) | 49 (19) | 64 (44) | 66 (47) | 89 (57) |
| UM (# of females) | 21 (16) | 61 (19) | 37 (20) | 50 (21) | 41 (30) |
| UTS (# of females) | 38 (24) | 26 (11) | 19 (11) | 29 (19) | 22 (11) |
| YU (# of females) | 46 (24) | 54 (15) | 36 (18) | 71 (47) | 46 (28) |
| Trials used | 138.7 (12.4) | 137.4 (14.2) | 138.5 (12.0) | 140.9 (10.9) | 139.0 (13.3) |
| GAF | 86.71 (6.61) | 49.22 (12.2) | 60.87 (12.5) | 74.13 (14.1) | 75.86 (13.5) |
| PANSS-positive | – | 17.01 (5.49, n = 220) | 12.61 (4.29, n = 176) | 16.07 (5.14, n = 30) | 13.80 (5.80, n = 25) |
| PANSS-negative | – | 16.98 (5.72, n = 220) | 12.13 (3.78, n = 176) | 13.67 (4.27, n = 30) | 12.76 (4.88, n = 25) |
| PANSS-general | – | 32.90 (8.88, n = 220) | 28.48 (8.02, n = 176) | 30.70 (8.04, n = 30) | 31.00 (7.34, n = 25) |
| MADRS | – | 8.850 (7.81, n = 207) | 10.71 (9.32, n = 168) | 6.529 (8.05, n = 51) | 7.333 (8.29, n = 39) |
| Young Mania Scale | – | 5.636 (5.81, n = 221) | 5.102 (5.80, n = 176) | 3.608 (4.47, n = 51) | 4.155 (6.29, n = 38) |
Note. Symptom scores are provided for probands and the subset of relatives of SZ and BD with a lifetime history of psychosis. HU = Harvard University; UIC = University of Illinois, Chicago; YU = Yale University; UTS = University of Texas Southwestern; UM = University of Maryland; GAF = Global Assessment of Functioning; PANSS = Positive and Negative Symptom Scale; MADRS = Montgomery-Åsberg Depression Rating Scale; APS = antipsychotic medication.