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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Immunol Rev. 2017 Jan;275(1):296–312. doi: 10.1111/imr.12511

Figure 4. VRC01 serum concentrations needed to protect against SHIV infection.

Figure 4

The neutralization sensitivity (IC50) of a panel of 177 HIV-1 strains to VRC01 is shown (red) along with the sensitivity of two SHIVs (SHIVSF162P3 and SHIVBaL.P4) (black). The plasma concentration of VRC01 needed to protect 50% of animals (EC50) after mucosal challenge is indicated for each SHIV.