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. 2017 Feb 16;17:54. doi: 10.1186/s12862-017-0901-7

Fig. 2.

Fig. 2

Graphical representation of distribution of selection pressure in Certatiodactyl Toll-like receptors. The majority of sites are under purifying selection. However positive selection is likely to occur in the ecto-domain (ECD) (brown-highlighted) than the transmembrane (TM) and Toll/Interleukin receptor (TIR) domain. Only TLR2-5 and TLR10 are presented for which clear positional demarcation of all three TLR domains was confidently predicted by SMART using cattle TLR as reference