Table 4.
Linear Regression Analysis of Plasma Cytokines and Asthma in 577 Study Participants
| Unadjusted | Adjusteda | |||
|---|---|---|---|---|
| Plasma cytokine | OR (95% CI) | P | OR (95% CI) | P |
| IL-1β | 1.65 (1.21 to 2.26) | 0.001 | 1.63 (1.18 to 2.25) | 0.003 |
| IL-4 | 0.95 (0.80 to 1.13) | 0.56 | 0.98 (0.82 to 1.17) | 0.82 |
| IL-6 | 1.09 (0.81 to 1.47) | 0.56 | 1.23 (0.90 to 1.68) | 0.20 |
| IL-10 | 1.13 (0.96 to 1.33) | 0.13 | 1.18 (0.994 to 1.39) | 0.06 |
| IL-17A | 1.17 (0.97 to 1.42) | 0.11 | 1.17 (0.96 to 1.43) | 0.13 |
| IL-17F | 0.82 (0.71 to 0.96) | 0.01 | 0.86 (0.74 to 1.02) | 0.07 |
| IL-21 | 1.19 (0.96 to 1.48) | 0.12 | 1.22 (0.97 to 1.53) | 0.09 |
| IL-22 | 1.28 (1.08 to 1.53) | 0.006 | 1.32 (1.10 to 1.58) | 0.003 |
| IL-23 | 0.83 (0.62 to 1.13) | 0.23 | 0.84 (0.61 to 1.14) | 0.26 |
| IL-25 | 1.05 (0.70 to 1.57) | 0.83 | 1.19 (0.78 to 1.82) | 0.41 |
| IL-31 | 1.16 (0.97 to 1.38) | 0.11 | 1.20 (1.00 to 1.44) | 0.048 |
| IL-33 | 1.45 (1.13 to 1.87) | 0.003 | 1.45 (1.13 to 1.87) | 0.004 |
| IFN-γ | 0.87 (0.75 to 1.01) | 0.07 | 0.92 (0.79 to 1.07) | 0.29 |
| TNFα | 1.28 (0.64 to 2.55) | 0.48 | 1.51 (0.70 to 3.24) | 0.29 |
Bold indicates statistical significance at alpha level 0.05.
a
Adjusted for age, gender, household income, and current ETS exposure.