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. 2017 Feb 15;34(4):890–905. doi: 10.1089/neu.2016.4508

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© Laura B. Tucker, et al. 2016; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.

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FIG. 1. — Controlled cortical impact (CCI)-induced brain injury. Sections shown were stained with cresyl violet and represent the median lesion volume as assessed 23 days following CCI (A). Considerable damage to the ipsilateral cortex and hippocampus resulted from the severe level of CCI (velocity 5 m/sec, depth 2.0 mm). Mild CCI (velocity 5 m/sec, depth 1.0 mm) resulted in little obvious damage. Analysis of lesion volumes (B) showed that mice that sustained both mild and severe CCI had significantly greater lesion volumes than sham-control mice. Horizontal bars in A represent 1 mm. The pound sign (#) represents a significant effect of the indicated injury group compared with sham controls.